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Doctors and scientists from three countries have set a world first in successfully transplanting an artificial organ using stem cells and a donated trachea.
The new organ transplanted into a 30-year-old woman, Claudia Castillo, with end-stage bronchomalacia after contracting TB, has shown no signs of rejection four months later, reports the Lancet online today.

After multiple treatments [...]

What is Bronchomalacia?Bronchomalacia means ‘floppiness’ of some part of the Bronchi (the medium sized airways). This condition is not common but by no means rare. What causes Bronchomalacia?It can occur as an isolated congenital abnormality or associated with other conditions especially congenital heart disease.What are the symptoms? a cough a wheeze, varying degrees of shortness [...]

A bronchoscopy or “bronch” as it is often referred to by patients, is a procedure performed by a pulmonologist when a closer look of the airways and lungs is needed. This helps the doctor determine the progression of lung disease. Brochoscopy’s are useful for finding infection or physical problems within the lungs or airways.A [...]

Laryngomalacia, bronchomalacia, and tracheomalacia are commonly seen in pediatric respiratory medicine, yet their patterns and associations with other conditions are not well-understood. We prospectively video-recorded bronchoscopic data and clinical information from referred patients over a 10-year period and defined aspects of interrelationships and associations.
Two hundred and ninety-nine cases of malacia disorders (34%) were observed in [...]

Tracheobronchial obstruction is infrequent in the pediatric age group but it is associated with significant morbidity and mortality. The purpose of this study is to review the results of a single institution experience with endoscopic stent placement in children with benign tracheobronchial obstruction, and with special concern on safety and clinical effectiveness. Materials and methods: [...]

Tracheobronchomalacia (TBM) disorders in children have never been studied using quantified measurements and validated clinical outcome measures. The objectives of the study were to prospectively examine the relationship between malacia lesions and their respiratory illness profiles The site of malacia lesions (eg, tracheomalacia, TBM, and bronchomalacia) were determined, measured, and related to the respective cricoid [...]

The term “malacia” refers to softness; in medical terminology, it refers to weakness of bone or cartilage. Laryngomalacia is the most common congenital abnormality of the larynx, and the patient may experience recurrent aspiration. Tracheomalacia refers to tracheal weakness and usually causes airway collapse as a result of cartilage defect. Bronchomalacia describes the weakness and [...]

We reviewed our experience on tracheomalacia (TM) and bronchomalacia (BM) in children who presented with chronic respiratory problems and evaluated their clinical and radiologic characteristics and their associations with other disorders. There were 26 males and 8 females with a median age of 9 months. The main symptoms were wheezing, persistent or recurrent pneumonia, and [...]

Laryngomalacia, bronchomalacia, and tracheomalacia are commonly seen in pediatric respiratory medicine, yet their patterns and associations with other conditions are not well-understood. We prospectively video-recorded bronchoscopic data and clinical information from referred patients over a 10-year period and defined aspects of interrelationships and associations.
Two hundred and ninety-nine cases of malacia disorders (34%) were observed in [...]